Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 218
interventional 174
Observational 37
Registry 7

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 78
Drug|Other 23
Drug|Procedure 10
Biological|Other 8
Biological 7
Drug|placebo 5
Radiation 5
Biological|Drug|Other 4
Biological|Drug|Procedure 4
Device 3
Drug|Other|Procedure 3
Other 3
Biological|Drug 2
Biological|Drug|Procedure|Radiation 2
Biological|Procedure 2
Device|Drug 2
Procedure 2
Biological|Drug|Genetic 1
Biological|Drug|Genetic|Other 1
Biological|Drug|Other|Procedure|Radiation 1
Combination Product|Drug 1
Device|Drug|Procedure 1
Device|Radiation 1
Drug|Genetic 1
Drug|Other|placebo 1
Drug|Procedure|Radiation 1
Genetic 1
Other|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 97
China 11
France 11
United States|Puerto Rico 11
NA 6
United States|Canada 5
Italy 3
United States|Australia|Canada 3
United States|Canada|Puerto Rico 3
Canada 2
Korea, Republic of 2
United States|Australia|Canada|Puerto Rico 2
Belgium|Denmark|France|Netherlands|Portugal|Saudi Arabia|Slovenia|United Kingdom 1
Brazil 1
Czechia|Hungary|Poland|Sweden 1
Finland|Korea, Republic of|New Zealand|Spain 1
France|Germany|Italy|Spain|United Kingdom 1
Germany 1
Ireland|United Kingdom 1
Israel 1
Italy|Norway 1
Italy|Spain|United Kingdom 1
Taiwan 1
United States|Australia|Canada|Netherlands|Puerto Rico|Switzerland 1
United States|Australia|Canada|New Zealand|Puerto Rico 1
United States|Canada|France|Italy|Spain|Switzerland|United Kingdom 1
United States|Chile 1
United States|France|Germany|Italy|Spain|United Kingdom 1
United States|France|Germany|Spain 1
United States|Lebanon 1

Sites per Study

Site_count Study_Count
1 87
2 12
3 5
4 8
5 3
6 2
8 2
9 2
10 2
11 3
12 1
13 2
15 3
16 1
17 2
18 1
19 3
20 1
23 1
24 2
25 2
28 1
30 1
31 1
37 1
76 2
88 1
93 1
105 2
106 1
111 2
112 1
113 1
114 1
116 1
117 1
118 1
119 1
130 1
141 1
143 1
148 1
155 1
161 1
167 1
382 1
651 1

Phase

Phase Study_Count
Phase 2 84
Phase 1 41
Phase 1/Phase 2 18
N/A 14
Phase 3 8
Phase 2/Phase 3 4
Phase 4 3
Early Phase 1 2

Number of Arms

Number_of_Arms Count_of_Studies
1 100
2 38
3 6
4 4
5 1
6 1
7 1
8 1
10 2
12 3
NA 17

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 12.00 12.0000 11.00000 15.00000 10.0000 11.00 6.000 150.0000
1st Qu. 15.25 62.5000 19.00000 23.50000 38.7500 30.50 193.250 275.0000
Median 18.50 99.5000 26.00000 45.50000 49.0000 88.50 239.500 400.0000
Mean 18.50 187.5714 37.20513 78.55556 97.8125 103.25 264.875 661.3333
3rd Qu. 21.75 196.0000 45.50000 77.25000 116.5000 161.25 274.500 917.0000
Max. 25.00 763.0000 120.00000 352.00000 1500.0000 225.00 711.000 1434.0000

Trial Group Type

group_type Group_Count
Experimental 257
NA 17
Active Comparator 15
Other 8
Placebo Comparator 6
No Intervention 5
Sham Comparator 1

Intervention Model

intervention_model Study_Count
Single Group Assignment 116
Parallel Assignment 35
NA 12
Sequential Assignment 7
Crossover Assignment 4

Primary Purpose

primary_purpose Study_Count
Treatment 159
Diagnostic 5
Prevention 4
Supportive Care 3
Health Services Research 1
Other 1
Screening 1

Observational Studies

Studies by Country

Country Study_Count
United States 16
Hong Kong 2
Italy 2
NA 2
China 1
Egypt 1
France 1
Germany 1
Germany|Italy|Sweden 1
Hungary|Norway|Poland|Sweden 1
India 1
Korea, Republic of 1
Spain 1
United Kingdom 1
United States|Australia|Canada|New Zealand|Puerto Rico 1
United States|Australia|Canada|Puerto Rico 1
United States|Canada 1
United States|Canada|Puerto Rico 1
United States|Puerto Rico 1

Sites per Study

Site_count Study_Count
1 26
2 3
3 2
5 1
66 1
79 1
92 1
164 1
180 1

Enrollment Metrics

Measure Observational
Min 1.0000
1st Qu 33.0000
Median 118.0000
Mean 752.2778
3rd Qu 262.7500
Max 10000.0000

Observation Model

observational_model Study_Count
Cohort 18
Case-Only 8
NA 4
Other 3
Case Control 2
Case-Control 1
Family-Based 1

Time Perspective

time_perspective Study_Count
Prospective 18
Retrospective 16
NA 2
Cross-Sectional 1

Registries

Studies by Country

Country Study_Count
China 5
Argentina|Brazil|Costa Rica|France|Italy|Mexico|Peru|Spain 1
Spain 1

Sites per Study

Site_count Study_Count
1 4
2 1
9 1
17 1

Enrollment Metrics

Measure Registries
Min 40.0000
1st Qu 40.0000
Median 50.0000
Mean 764.2857
3rd Qu 90.0000
Max 5000.0000

Registry Model

observational_model Study_Count
Cohort 5
Case-Only 2

Time Perspective

time_perspective Study_Count
Prospective 6
Other 1

Follow-up

target_duration Study_Count
2 Years 3
1 Year 1
12 Months 1
3 Years 1
30 Months 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT04195555 Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial) https://ClinicalTrials.gov/show/NCT04195555 Recruiting National Cancer Institute (NCI) 2025-12-31
NCT03698994 Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial) https://ClinicalTrials.gov/show/NCT03698994 Recruiting National Cancer Institute (NCI) 2025-12-31
NCT03526250 Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial) https://ClinicalTrials.gov/show/NCT03526250 Recruiting National Cancer Institute (NCI) 2025-06-30
NCT03449108 LN-145 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas https://ClinicalTrials.gov/show/NCT03449108 Recruiting M.D. Anderson Cancer Center 2020-12-31
NCT03635632 C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N) https://ClinicalTrials.gov/show/NCT03635632 Recruiting Baylor College of Medicine 2022-06-30
NCT03360760 Timing of Surgery in Nonmetastatic Osteosarcoma of the Pelvis and Sacrum https://ClinicalTrials.gov/show/NCT03360760 Recruiting Peking University People’s Hospital 2020-02-29
NCT03359018 Apatinib Plus Anti-PD1 Therapy for Advanced Osteosarcoma https://ClinicalTrials.gov/show/NCT03359018 Completed Peking University People’s Hospital 2019-10-22
NCT03320330 Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors https://ClinicalTrials.gov/show/NCT03320330 Active, not recruiting Children’s Oncology Group 2021-09-19
NCT03277924 Trial of Sunitinib Plus Nivolumab After Standard Treatment in Advanced Soft Tissue and Bone Sarcomas https://ClinicalTrials.gov/show/NCT03277924 Recruiting Grupo Espanol de Investigacion en Sarcomas 2022-09-30
NCT03244020 Low Molecular Weight Heparin (LMWH) vs Aspirin for Venous Thromboembolism (VTE) Prophylaxis in Orthopaedic Oncology https://ClinicalTrials.gov/show/NCT03244020 Enrolling by invitation Massachusetts General Hospital 2023-12-31
NCT03154190 Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer https://ClinicalTrials.gov/show/NCT03154190 Recruiting Stanford University 2020-11-30
NCT03139318 Phase I Clinical Trial of GRID Therapy in Pediatric Osteosarcoma of the Extremity https://ClinicalTrials.gov/show/NCT03139318 Recruiting University of Arkansas 2021-06-30
NCT03063983 Clinical Trial Evaluating Metronomic Chemotherapy in Patients With Metastatic Osteosarcoma https://ClinicalTrials.gov/show/NCT03063983 Recruiting Grupo de Apoio ao Adolescente e a Crianca com Cancer 2019-01-02
NCT03013127 A Study of Pembrolizumab in Patients With Relapsed Or Metastatic Osteosarcoma Not Eligible for Curative Surgery https://ClinicalTrials.gov/show/NCT03013127 Active, not recruiting Oslo University Hospital 2018-11-26
NCT03233204 Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial) https://ClinicalTrials.gov/show/NCT03233204 Recruiting National Cancer Institute (NCI) 2024-09-30
NCT02982941 Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumors https://ClinicalTrials.gov/show/NCT02982941 Completed MacroGenics 2019-05-22
NCT02945800 Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma https://ClinicalTrials.gov/show/NCT02945800 Recruiting H. Lee Moffitt Cancer Center and Research Institute 2020-12-31
NCT02856048 Co-treatment With GnRH Analogs on the Ovarian Reserve in Young Women Treated With Alkylating Agents for Cancer https://ClinicalTrials.gov/show/NCT02856048 Active, not recruiting Assistance Publique - Hôpitaux de Paris 2021-02-28
NCT03220035 Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial) https://ClinicalTrials.gov/show/NCT03220035 Recruiting National Cancer Institute (NCI) 2023-12-31
NCT02811523 In Vivo Lung Perfusion for Pulmonary Metastases of Sarcoma https://ClinicalTrials.gov/show/NCT02811523 Recruiting University Health Network, Toronto 2024-02-29
NCT03213704 Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial) https://ClinicalTrials.gov/show/NCT03213704 Recruiting National Cancer Institute (NCI) 2024-09-30
NCT03213678 PI3K/mTOR Inhibitor LY3023414 in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial) https://ClinicalTrials.gov/show/NCT03213678 Recruiting National Cancer Institute (NCI) 2024-09-30
NCT02711007 Apatinib for Advanced Osteosarcoma After Failure of Standard Multimodal Therapy https://ClinicalTrials.gov/show/NCT02711007 Completed Peking University People’s Hospital 2017-12-30
NCT03213665 Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial) https://ClinicalTrials.gov/show/NCT03213665 Recruiting National Cancer Institute (NCI) 2024-09-30
NCT02644460 Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors https://ClinicalTrials.gov/show/NCT02644460 Recruiting Emory University 2020-12-31
NCT03213652 Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial) https://ClinicalTrials.gov/show/NCT03213652 Recruiting National Cancer Institute (NCI) 2024-09-30
NCT02581384 Stereotactic Body Radiotherapy (SBRT) for Pulmonary Metastases in Ewing Sarcoma, Rhabdomyosarcoma, and Wilms Tumors https://ClinicalTrials.gov/show/NCT02581384 Active, not recruiting Dana-Farber Cancer Institute 2025-02-28
NCT03210714 Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial) https://ClinicalTrials.gov/show/NCT03210714 Recruiting National Cancer Institute (NCI) 2024-12-31
NCT03155620 Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial) https://ClinicalTrials.gov/show/NCT03155620 Recruiting National Cancer Institute (NCI) 2027-09-30
NCT00840047 Methionine PET/CT Studies In Patients With Cancer https://ClinicalTrials.gov/show/NCT00840047 Recruiting St. Jude Children’s Research Hospital 2027-07-27
NCT02536183 A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric Refractory Solid Tumors https://ClinicalTrials.gov/show/NCT02536183 Recruiting Children’s National Research Institute 2020-10-31
NCT02520128 A Study of IMRT in Primary Bone and Soft Tissue Sarcoma https://ClinicalTrials.gov/show/NCT02520128 Recruiting University College, London 2020-03-31
NCT02517918 Metronomic Chemotherapy in Patients With Advanced Solid Tumor With Bone Metastasis and Advanced Pretreated Osteosarcoma https://ClinicalTrials.gov/show/NCT02517918 Recruiting Institut Bergonié 2021-01-31
NCT02508038 Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors https://ClinicalTrials.gov/show/NCT02508038 Recruiting University of Wisconsin, Madison 2021-05-31
NCT02502786 Humanized Monoclonal Antibody 3F8 (Hu3F8) With Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) in the Treatment of Recurrent Osteosarcoma https://ClinicalTrials.gov/show/NCT02502786 Recruiting Memorial Sloan Kettering Cancer Center 2021-07-31
NCT02500797 Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery https://ClinicalTrials.gov/show/NCT02500797 Active, not recruiting National Cancer Institute (NCI) 2019-04-01
NCT02487979 Glembatumumab Vedotin in Treating Patients With Recurrent or Refractory Osteosarcoma https://ClinicalTrials.gov/show/NCT02487979 Completed National Cancer Institute (NCI) 2017-06-30
NCT02484443 Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma https://ClinicalTrials.gov/show/NCT02484443 Active, not recruiting National Cancer Institute (NCI) 2020-03-31
NCT02470091 Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma https://ClinicalTrials.gov/show/NCT02470091 Active, not recruiting Children’s Oncology Group 2019-12-31
NCT02432274 Study of Lenvatinib in Children and Adolescents With Refractory or Relapsed Solid Malignancies and Young Adults With Osteosarcoma https://ClinicalTrials.gov/show/NCT02432274 Completed Eisai Inc. 2019-07-31
NCT02429973 Trial With Gemcitabine and Rapamycin in Second Line of Metastatic Osteosarcoma https://ClinicalTrials.gov/show/NCT02429973 Completed Broto, Javier Martín, M.D. 2014-12-31
NCT02390843 Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors https://ClinicalTrials.gov/show/NCT02390843 Completed Emory University 2019-09-22
NCT02389244 A Phase II Study Evaluating Efficacy and Safety of Regorafenib in Patients With Metastatic Bone Sarcomas https://ClinicalTrials.gov/show/NCT02389244 Recruiting UNICANCER 2022-09-30
NCT02384473 Real-Time Contrast-Enhanced Ultrasonography and Shear Wave Elastography in Predicting Treatment Response in Patients With Soft Tissue Sarcoma https://ClinicalTrials.gov/show/NCT02384473 Active, not recruiting University of Southern California 2019-12-24
NCT02357810 Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas https://ClinicalTrials.gov/show/NCT02357810 Recruiting Northwestern University 2021-07-31
NCT02304458 Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas https://ClinicalTrials.gov/show/NCT02304458 Active, not recruiting National Cancer Institute (NCI) 2021-01-31
NCT02301039 SARC028: A Phase II Study of the Anti-PD1 Antibody Pembrolizumab (MK-3475) in Patients With Advanced Sarcomas https://ClinicalTrials.gov/show/NCT02301039 Active, not recruiting Sarcoma Alliance for Research through Collaboration 2018-11-30
NCT02243605 Cabozantinib S-malate in Treating Patients With Relapsed Osteosarcoma or Ewing Sarcoma https://ClinicalTrials.gov/show/NCT02243605 Active, not recruiting National Cancer Institute (NCI) 2019-06-30
NCT02223052 Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies https://ClinicalTrials.gov/show/NCT02223052 Completed Celgene 2018-06-11
NCT02180867 Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery https://ClinicalTrials.gov/show/NCT02180867 Active, not recruiting National Cancer Institute (NCI) 2019-06-30
NCT02162732 Molecular-Guided Therapy for Childhood Cancer https://ClinicalTrials.gov/show/NCT02162732 Active, not recruiting Spectrum Health Hospitals 2020-06-30
NCT02100891 Phase 2 STIR Trial: Haploidentical Transplant and Donor Natural Killer Cells for Solid Tumors https://ClinicalTrials.gov/show/NCT02100891 Recruiting Medical College of Wisconsin 2020-12-31
NCT02097238 Eribulin Mesylate in Treating Patients With Recurrent or Refractory Osteosarcoma https://ClinicalTrials.gov/show/NCT02097238 Completed National Cancer Institute (NCI) 2015-06-30
NCT02094625 NAC to Prevent Cisplatin-induced Hearing Loss https://ClinicalTrials.gov/show/NCT02094625 Recruiting Children’s Hospital Los Angeles 2021-01-31
NCT02076906 MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors https://ClinicalTrials.gov/show/NCT02076906 Recruiting Children’s National Research Institute 2020-10-31
NCT02013336 Phase 1 Study of MM-398 Plus Cyclophosphamide in Pediatric Solid Tumors https://ClinicalTrials.gov/show/NCT02013336 Recruiting South Plains Oncology Consortium 2020-12-31
NCT01987102 Investigation of [6R] 5,10-methylenetetrahydrofolate as Rescue Therapy for Osteosarcoma Patients Treated With HDMTX. https://ClinicalTrials.gov/show/NCT01987102 Completed Isofol Medical AB 2017-01-03
NCT01962103 Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors https://ClinicalTrials.gov/show/NCT01962103 Completed Celgene 2017-12-05
NCT01953900 iC9-GD2-CAR-VZV-CTLs/Refractory or Metastatic GD2-positive Sarcoma and Neuroblastoma https://ClinicalTrials.gov/show/NCT01953900 Active, not recruiting Baylor College of Medicine 2021-04-30
NCT04351308 Comparison of MAPI+Camrelizumab Versus API+Apatinib Versus MAPI in Patients With a Poor Response to Preoperative Chemotherapy for Newly Diagnosed High-grade Osteosarcoma https://ClinicalTrials.gov/show/NCT04351308 Recruiting Peking University People’s Hospital 2022-09-01
NCT01848457 Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma Therapy https://ClinicalTrials.gov/show/NCT01848457 Completed Children’s Hospital of Philadelphia 2016-01-04
NCT01833520 Phase I Dose Escalation of Monthly Intravenous Ra-223 Dichloride in Osteosarcoma https://ClinicalTrials.gov/show/NCT01833520 Active, not recruiting M.D. Anderson Cancer Center 2020-10-31
NCT01830153 RAD001 in Advanced Sarcoma https://ClinicalTrials.gov/show/NCT01830153 Completed Asan Medical Center 2013-01-31
NCT01807468 Haploidentical Stem Cell Transplantation and NK Cell Therapy in Patients With High-risk Solid Tumors https://ClinicalTrials.gov/show/NCT01807468 Active, not recruiting Samsung Medical Center 2015-12-31
NCT01804374 Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable Osteosarcoma https://ClinicalTrials.gov/show/NCT01804374 Completed Italian Sarcoma Group 2014-12-31
NCT01803152 Dendritic Cell Vaccine for Children and Adults With Sarcoma https://ClinicalTrials.gov/show/NCT01803152 Active, not recruiting University of Miami 2019-09-10
NCT01674101 Effects of Preoperative Physical Therapy in Patients With Lower Extremity Malignancy https://ClinicalTrials.gov/show/NCT01674101 Completed St. Jude Children’s Research Hospital 2015-11-30
NCT01669369 Clinical Trial of Lithium Carbonate Combined With Neo-adjuvant Chemotherapy to Treat Osteosarcoma https://ClinicalTrials.gov/show/NCT01669369 Recruiting Sun Yat-sen University 2023-12-31
NCT01661400 Anti-Angiogenic Therapy Post Transplant (ASCR) for Pediatric Solid Tumors https://ClinicalTrials.gov/show/NCT01661400 Recruiting Washington University School of Medicine 2022-11-23
NCT01650090 Phase 2 Study of Inhaled Lipid Cisplatin in Pulmonary Recurrent Osteosarcoma https://ClinicalTrials.gov/show/NCT01650090 Completed Eleison Pharmaceuticals LLC. 2018-11-30
NCT01614795 Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma https://ClinicalTrials.gov/show/NCT01614795 Completed National Cancer Institute (NCI) 2014-04-01
NCT01590069 Aerosolized Aldesleukin in Treating Patients With Lung Metastases https://ClinicalTrials.gov/show/NCT01590069 Active, not recruiting M.D. Anderson Cancer Center 2020-06-30
NCT01588522 Compound 31543 (Calcitriol, USP) in Patients Receiving Taxane-based Chemotherapy Regimens for Advanced or Recurrent Disease https://ClinicalTrials.gov/show/NCT01588522 Completed Berg, LLC 2017-01-31
NCT01553539 Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery https://ClinicalTrials.gov/show/NCT01553539 Completed Wake Forest University Health Sciences 2013-01-31
NCT01532687 Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma https://ClinicalTrials.gov/show/NCT01532687 Active, not recruiting OHSU Knight Cancer Institute 2020-06-30
NCT01518413 Dose Escalation Study of Sorafenib and Irinotecan Combination Therapy in Pediatric Patients With Solid Tumors https://ClinicalTrials.gov/show/NCT01518413 Completed Children’s National Research Institute 2015-01-31
NCT01459484 ABCB1/P-glycoprotein Expression as Biologic Stratification Factor for Patients With Non Metastatic Osteosarcoma https://ClinicalTrials.gov/show/NCT01459484 Active, not recruiting Italian Sarcoma Group 2021-03-31
NCT01353625 Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies. https://ClinicalTrials.gov/show/NCT01353625 Active, not recruiting Celgene 2020-12-28
NCT01336803 Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRI https://ClinicalTrials.gov/show/NCT01336803 Completed Stanford University 2014-07-31
NCT04294511 Study of Camrelizumab in Combination With Neoadjuvant Chemotherapy in the Treatment of Osteosarcoma https://ClinicalTrials.gov/show/NCT04294511 Recruiting Sun Yat-sen University 2021-03-16
NCT04183062 BIO-11006 for Osteosarcoma and Ewing’s Sarcoma Lung Metastases https://ClinicalTrials.gov/show/NCT04183062 Recruiting Nicklaus Children’s Hospital f/k/a Miami Children’s Hospital 2022-11-04
NCT04154189 A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory Osteosarcoma https://ClinicalTrials.gov/show/NCT04154189 Recruiting Eisai Inc. 2022-12-31
NCT04040205 Abemaciclib for Treatment of Advanced Bone and Soft Tissue Sarcoma Identified as Having CDK Pathway Alteration https://ClinicalTrials.gov/show/NCT04040205 Recruiting Medical College of Wisconsin 2023-09-01
NCT03960177 Glucarpidase After High-Dose Methotrexate in Patients With Osteosarcoma https://ClinicalTrials.gov/show/NCT03960177 Recruiting OHSU Knight Cancer Institute 2020-10-01
NCT03932071 Zoledronic Acid in Decrease the Lung Metastatic Rate of Osteosarcoma https://ClinicalTrials.gov/show/NCT03932071 Recruiting Second Affiliated Hospital, School of Medicine, Zhejiang University 2020-01-01
NCT03909776 Transcatheter Intra-arterial Limb Infusion of Cisplatin for Extremity Osteosarcoma https://ClinicalTrials.gov/show/NCT03909776 Completed Peking University People’s Hospital 2019-04-01
NCT03900793 Losartan + Sunitinib in Treatment of Osteosarcoma https://ClinicalTrials.gov/show/NCT03900793 Recruiting University of Colorado, Denver 2024-02-29
NCT03860207 Study of the Safety and Efficacy of Humanized 3F8 Bispecific Antibody (Hu3F8-BsAb) in Patients With Relapsed/Refractory Neuroblastoma, Osteosarcoma and Other Solid Tumor Cancers https://ClinicalTrials.gov/show/NCT03860207 Recruiting Memorial Sloan Kettering Cancer Center 2022-02-28
NCT03718091 M6620 (VX-970) in Selected Solid Tumors https://ClinicalTrials.gov/show/NCT03718091 Recruiting Massachusetts General Hospital 2022-04-30
NCT03676985 A Clinical Study of PD-L1 Antibody ZKAB001(Drug Code) in Limited Stage of High-grade Osteosarcoma https://ClinicalTrials.gov/show/NCT03676985 Recruiting Lee’s Pharmaceutical Limited 2020-02-14
NCT03643133 Mifamurtide Combined With Post-operative Chemotherapy for Newly Diagnosed High Risk Osteosarcoma Patients https://ClinicalTrials.gov/show/NCT03643133 Recruiting UNICANCER 2022-10-31
NCT03628209 Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent, Resectable Osteosarcoma https://ClinicalTrials.gov/show/NCT03628209 Recruiting H. Lee Moffitt Cancer Center and Research Institute 2021-07-31
NCT03618381 EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults https://ClinicalTrials.gov/show/NCT03618381 Recruiting Seattle Children’s Hospital 2021-06-30
NCT03598595 Gemcitabine, Docetaxel, and Hydroxychloroquine in Treating Participants With Recurrent or Refractory Osteosarcoma https://ClinicalTrials.gov/show/NCT03598595 Recruiting M.D. Anderson Cancer Center 2022-03-02
NCT03496402 Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults (MICCHADO) https://ClinicalTrials.gov/show/NCT03496402 Recruiting Institut Curie 2025-04-01
NCT03478462 Dose Escalation Study of CLR 131 in Children and Adolescents With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma https://ClinicalTrials.gov/show/NCT03478462 Recruiting Cellectar Biosciences, Inc. 2020-09-30
NCT03462316 NY-ESO-1-specific T Cell Receptor (TCR) T Cell in Sarcoma https://ClinicalTrials.gov/show/NCT03462316 Recruiting Sun Yat-sen University 2020-10-20
NCT03449901 ADI-PEG 20 in Combination With Gemcitabine and Docetaxel for the Treatment of Soft Tissue Sarcoma, Osteosarcoma, Ewing’s Sarcoma, and Small Cell Lung Cancer https://ClinicalTrials.gov/show/NCT03449901 Recruiting Washington University School of Medicine 2021-05-09
NCT03425279 CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With Solid Tumors https://ClinicalTrials.gov/show/NCT03425279 Recruiting BioAtla, LLC 2022-01-31
NCT01241162 Decitabine Followed by a Cancer Antigen Vaccine for Patients With Neuroblastoma and Sarcoma https://ClinicalTrials.gov/show/NCT01241162 Completed University of Louisville 2016-10-31
NCT01176981 Outpatient Administration of High Dose Methotrexate (HD MTX) in Patients With Osteosarcoma https://ClinicalTrials.gov/show/NCT01176981 Completed The Hospital for Sick Children 2016-10-31
NCT01154816 Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia https://ClinicalTrials.gov/show/NCT01154816 Completed Children’s Oncology Group 2015-12-31
NCT01154452 Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma https://ClinicalTrials.gov/show/NCT01154452 Completed National Cancer Institute (NCI) 2015-02-28
NCT01091883 Study Comparing the Safety and Effectiveness of Magnetic Resonance Guided Focused Ultrasound (MRgFUS) and External Beam Radiation (EBRT) for Treatment of Metastatic Bone Tumors and Multiple Myeloma https://ClinicalTrials.gov/show/NCT01091883 Completed InSightec 2019-01-31
NCT01085565 Focused Ultrasound Surgery in the Treatment of Pain Resulting From Metastatic Bone Tumors With the ExAblate 2100 Conformal Bone System https://ClinicalTrials.gov/show/NCT01085565 Completed InSightec 2013-03-31
NCT01016015 Temsirolimus and Cixutumumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Soft Tissue Sarcoma or Bone Sarcoma https://ClinicalTrials.gov/show/NCT01016015 Completed National Cancer Institute (NCI) 2014-07-31
NCT01005043 Therapy Trial to Determine the Safety and Efficacy of Heavy Ion Radiotherapy in Patients With Osteosarcoma https://ClinicalTrials.gov/show/NCT01005043 Completed University Hospital Heidelberg 2018-08-01
NCT00978471 Adjuvant High-Dose Thiotepa and Stem Cell Rescue Associated With Conventional Chemotherapy in Relapsed Osteosarcoma https://ClinicalTrials.gov/show/NCT00978471 Completed Centre Leon Berard 2018-10-29
NCT00931931 HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors https://ClinicalTrials.gov/show/NCT00931931 Completed Nationwide Children’s Hospital 2018-03-19
NCT00889057 Sorafenib in Relapsed High Grade Osteosarcoma https://ClinicalTrials.gov/show/NCT00889057 Completed Italian Sarcoma Group 2010-12-31
NCT00831844 Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors https://ClinicalTrials.gov/show/NCT00831844 Completed National Cancer Institute (NCI) 2013-04-30
NCT03742193 Pulmonary Resectable Metastases of Osteosarcoma With Apatinib and CHemotherapy https://ClinicalTrials.gov/show/NCT03742193 Recruiting Ruijin Hospital 2022-04-01
NCT03006848 A Phase II Trial of Avelumab in Patients With Recurrent or Progressive Osteosarcoma https://ClinicalTrials.gov/show/NCT03006848 Active, not recruiting St. Jude Children’s Research Hospital 2020-03-18
NCT01331135 Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors https://ClinicalTrials.gov/show/NCT01331135 Completed Emory University 2017-08-09
NCT02880319 Evaluating Stereotactic Body Radiation Therapy for Oligometastatic Disease of the Bone https://ClinicalTrials.gov/show/NCT02880319 Recruiting Dana-Farber Cancer Institute 2021-05-31
NCT02867592 Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors https://ClinicalTrials.gov/show/NCT02867592 Recruiting National Cancer Institute (NCI) 2020-09-30
NCT00802880 Dacarbazine for Metastatic Soft Tissue and Bone Sarcoma https://ClinicalTrials.gov/show/NCT00802880 Completed Washington University School of Medicine 2015-01-31
NCT02107963 A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors https://ClinicalTrials.gov/show/NCT02107963 Completed National Institutes of Health Clinical Center (CC) 2016-08-15
NCT02048371 SARC024: A Blanket Protocol to Study Oral Regorafenib in Patients With Selected Sarcoma Subtypes https://ClinicalTrials.gov/show/NCT02048371 Recruiting Sarcoma Alliance for Research through Collaboration 2021-08-31
NCT02415816 Diffusion Weighted Magnetic Resonance in Imaging Younger Patients With Newly Diagnosed Bone or Soft Tissue Sarcomas https://ClinicalTrials.gov/show/NCT02415816 Recruiting St. Jude Children’s Research Hospital 2022-03-31
NCT04055220 Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas https://ClinicalTrials.gov/show/NCT04055220 Recruiting Centre Leon Berard 2024-10-01
NCT00743509 A Phase II Study of Oral Cyclophosphamide and Sirolimus (OCR) in Advanced Sarcoma https://ClinicalTrials.gov/show/NCT00743509 Completed University of Michigan Rogel Cancer Center 2010-04-30
NCT00743496 A Phase I Trial Of The Humanized Anti-GD2 Antibody In Children And Adolescents With Neuroblastoma, Osteosarcoma, Ewing Sarcoma and Melanoma https://ClinicalTrials.gov/show/NCT00743496 Completed St. Jude Children’s Research Hospital 2014-04-01
NCT00742924 Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma https://ClinicalTrials.gov/show/NCT00742924 Completed Children’s Oncology Group 2012-04-30
NCT00720174 Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma https://ClinicalTrials.gov/show/NCT00720174 Completed National Cancer Institute (NCI) 2013-01-31
NCT00716976 Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy https://ClinicalTrials.gov/show/NCT00716976 Completed Children’s Oncology Group 2015-04-30
NCT00667342 A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma https://ClinicalTrials.gov/show/NCT00667342 Completed St. Jude Children’s Research Hospital 2014-08-31
NCT00645632 Combination Chemotherapy in Treating Patients Undergoing Surgery for Newly Diagnosed High-Grade Osteosarcoma https://ClinicalTrials.gov/show/NCT00645632 Completed Mayo Clinic 1995-01-31
NCT00634504 Open-label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without Voraxaze https://ClinicalTrials.gov/show/NCT00634504 Completed BTG International Inc. 2009-08-31
NCT00592293 Proton Radiation for the Treatment of Pediatric Bone and Non-Rhabdomyosarcoma Soft Tissue Sarcomas https://ClinicalTrials.gov/show/NCT00592293 Active, not recruiting Massachusetts General Hospital 2021-09-30
NCT00586846 Phase II Study of Chemotherapy and Pamidronate for the Treatment of Newly Diagnosed Osteosarcoma https://ClinicalTrials.gov/show/NCT00586846 Completed Memorial Sloan Kettering Cancer Center 2009-02-28
NCT00580385 Chemotherapy Resistance in Osteogenic Sarcoma and Other Solid Tumors https://ClinicalTrials.gov/show/NCT00580385 Active, not recruiting Memorial Sloan Kettering Cancer Center 2020-08-31
NCT00572130 Phase II Study of Intravenous Rexin-G in Osteosarcoma https://ClinicalTrials.gov/show/NCT00572130 Completed Epeius Biotechnologies 2010-07-31
NCT00538239 Ridaforolimus in Treatment of Sarcoma-SUCCEED (Sarcoma Multi-Center Clinical Evaluation of the Efficacy of Ridaforolimus)(8669-011 AM6) https://ClinicalTrials.gov/show/NCT00538239 Completed Merck Sharp & Dohme Corp. 2010-10-31
NCT00523419 Chemotherapy for Patients With Osteosarcoma https://ClinicalTrials.gov/show/NCT00523419 Completed Eli Lilly and Company 2009-06-30
NCT00520936 A Study of Pemetrexed in Children With Recurrent Cancer https://ClinicalTrials.gov/show/NCT00520936 Completed Eli Lilly and Company 2010-02-28
NCT00504140 Recombinant Interferon Alpha and Etoposide in Relapsed Osteosarcoma https://ClinicalTrials.gov/show/NCT00504140 Completed M.D. Anderson Cancer Center 2007-11-30
NCT00503295 Safety and Efficacy Study of REOLYSIN® in the Treatment of Bone and Soft Tissue Sarcomas Metastatic to the Lung https://ClinicalTrials.gov/show/NCT00503295 Completed Oncolytics Biotech 2011-02-28
NCT00470223 Combined Chemotherapy With or Without Zoledronic Acid for Patients With Osteosarcoma https://ClinicalTrials.gov/show/NCT00470223 Active, not recruiting UNICANCER 2015-12-31
NCT00020267 Vaccine Therapy in Treating Patients With Metastatic Cancer https://ClinicalTrials.gov/show/NCT00020267 Completed National Cancer Institute (NCI) NA
NCT00019630 Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors https://ClinicalTrials.gov/show/NCT00019630 Completed National Cancer Institute (NCI) NA
NCT00407433 Clinical Studies of Gemcitabine-Oxaliplatin https://ClinicalTrials.gov/show/NCT00407433 Completed Gustave Roussy, Cancer Campus, Grand Paris NA
NCT00331643 Ixabepilone in Treating Young Patients With Refractory Solid Tumors https://ClinicalTrials.gov/show/NCT00331643 Completed National Cancer Institute (NCI) 2007-10-31
NCT00330421 Sorafenib in Treating Patients With Soft Tissue Sarcomas (Extremity Sarcoma Closed to Entry as of 5/30/07) https://ClinicalTrials.gov/show/NCT00330421 Completed National Cancer Institute (NCI) 2007-12-31
NCT00245011 Samarium Sm 153 and Stem Cell Transplant Followed By Radiation Therapy Patients With Osteosarcoma https://ClinicalTrials.gov/show/NCT00245011 Completed Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 2008-10-31
NCT00187109 Recombinant Human Thrombopoietin in Children Receiving Ifosfamide, Carboplatin, and Etoposide Chemotherapy https://ClinicalTrials.gov/show/NCT00187109 Completed St. Jude Children’s Research Hospital 2007-02-28
NCT00180908 Comparison of High-Dose Methotrexate (HDM) Plus Doxorubicin to HDM Plus Etoposide-Ifosfamide in Osteosarcoma Children https://ClinicalTrials.gov/show/NCT00180908 Completed Gustave Roussy, Cancer Campus, Grand Paris NA
NCT00145639 Osteosarcoma1999-A Study Of Intensive Chemotherapy for Osteosarcoma https://ClinicalTrials.gov/show/NCT00145639 Completed St. Jude Children’s Research Hospital 2006-05-31
NCT00132158 ZD1839 and Oral Irinotecan in Treating Young Patients With Refractory Solid Tumors https://ClinicalTrials.gov/show/NCT00132158 Completed St. Jude Children’s Research Hospital 2011-10-31
NCT00119301 Methotrexate, Trimetrexate Glucuronate, and Leucovorin in Treating Patients With Refractory or Recurrent Osteosarcoma https://ClinicalTrials.gov/show/NCT00119301 Completed Memorial Sloan Kettering Cancer Center 2007-04-30
NCT00112463 Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma https://ClinicalTrials.gov/show/NCT00112463 Completed National Cancer Institute (NCI) 2008-10-23
NCT00102531 Inhalation SLIT Cisplatin (Liposomal) for the Treatment of Osteosarcoma Metastatic to the Lung https://ClinicalTrials.gov/show/NCT00102531 Completed Insmed Incorporated 2008-03-31
NCT00101270 Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas https://ClinicalTrials.gov/show/NCT00101270 Completed National Cancer Institute (NCI) 2007-09-30
NCT00093821 Tanespimycin in Treating Young Patients With Recurrent or Refractory Leukemia or Solid Tumors https://ClinicalTrials.gov/show/NCT00093821 Completed National Cancer Institute (NCI) 2007-08-31
NCT00093080 Study of AP23573/MK-8669 (Ridaforolimus), A Mammalian Target of Rapamycin (mTOR) Inhibitor, in Participants With Advanced Sarcoma (MK-8669-018 AM1)(COMPLETED) https://ClinicalTrials.gov/show/NCT00093080 Completed Merck Sharp & Dohme Corp. 2008-11-30
NCT00091182 Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatment https://ClinicalTrials.gov/show/NCT00091182 Completed National Cancer Institute (NCI) 2006-02-28
NCT00003776 Combination Chemotherapy and Surgery in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma https://ClinicalTrials.gov/show/NCT00003776 Completed Memorial Sloan Kettering Cancer Center 2000-03-31
NCT00005625 Ecteinascidin 743 in Treating Patients With Previously Treated Metastatic Osteosarcoma https://ClinicalTrials.gov/show/NCT00005625 Completed Memorial Sloan Kettering Cancer Center 2003-09-30
NCT00077454 Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid Tumors https://ClinicalTrials.gov/show/NCT00077454 Completed National Cancer Institute (NCI) 2007-09-30
NCT00003937 Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma https://ClinicalTrials.gov/show/NCT00003937 Completed Children’s Oncology Group 2004-03-31
NCT00073983 Gemcitabine and Docetaxel in Treating Patients With Recurrent Osteosarcoma (Closed to Accrual as of 12/21/06) or Ewing’s Sarcoma or Unresectable or Locally Recurrent Chondrosarcoma https://ClinicalTrials.gov/show/NCT00073983 Completed Sarcoma Alliance for Research through Collaboration 2010-01-31
NCT00066365 Inhaled Sargramostim in Treating Patients With First Pulmonary (Lung) Recurrence of Osteosarcoma https://ClinicalTrials.gov/show/NCT00066365 Completed Children’s Oncology Group 2010-07-31
NCT00030667 Imatinib Mesylate in Treating Patients With Relapsed or Refractory Solid Tumors of Childhood https://ClinicalTrials.gov/show/NCT00030667 Completed National Cancer Institute (NCI) 2005-12-31
NCT00002539 Combination Chemotherapy and Surgery With or Without G-CSF in Treating Patients With Osteosarcoma https://ClinicalTrials.gov/show/NCT00002539 Completed European Organisation for Research and Treatment of Cancer - EORTC 2002-10-31
NCT00004078 Irinotecan in Treating Children With Refractory Solid Tumors https://ClinicalTrials.gov/show/NCT00004078 Completed Children’s Oncology Group 2007-10-31
NCT00031915 Imatinib Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma or Bone Sarcoma https://ClinicalTrials.gov/show/NCT00031915 Completed National Cancer Institute (NCI) NA
NCT00023998 Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic Osteosarcoma https://ClinicalTrials.gov/show/NCT00023998 Completed National Cancer Institute (NCI) 2005-11-30
NCT00012181 Flavopiridol in Treating Children With Relapsed or Refractory Solid Tumors or Lymphomas https://ClinicalTrials.gov/show/NCT00012181 Completed National Cancer Institute (NCI) 2005-01-31
NCT00005033 Trastuzumab in Treating Patients With Recurrent Osteosarcoma https://ClinicalTrials.gov/show/NCT00005033 Completed National Cancer Institute (NCI) NA
NCT00004241 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Advanced Epithelial Cancer, Malignant Lymphoma, or Sarcoma https://ClinicalTrials.gov/show/NCT00004241 Completed National Cancer Institute (NCI) 2006-05-31
NCT00001436 A Phase I Study of OncoLAR® (Registered Trademark) (NSC 685403) With/Without Tamoxifen in Patients With Osteosarcoma https://ClinicalTrials.gov/show/NCT00001436 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001217 Osteosarcoma Study #2: A Randomized Trial of Pre-Surgical Chemotherapy vs. Immediate Surgery and Adjuvant Chemotherapy in the Treatment of Non-Metastatic Osteosarcoma. A Pediatric Oncology Group Phase III Study https://ClinicalTrials.gov/show/NCT00001217 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001209 A Pilot Study for the Treatment of Patients With Metastatic and High Risk Sarcomas and Primitive Neuroectodermal Tumors https://ClinicalTrials.gov/show/NCT00001209 Completed National Institutes of Health Clinical Center (CC) NA
NCT00038207 Liposomal Vincristine for Pediatric and Adolescent Patients With Relapsed Malignancies https://ClinicalTrials.gov/show/NCT00038207 Completed M.D. Anderson Cancer Center 2004-09-30

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03298971 The Impact of Cancer on the Physical and Psychosocial Well-being Among Childhood Osteosarcoma Survivors https://ClinicalTrials.gov/show/NCT03298971 Recruiting The University of Hong Kong 2020-09-01
NCT03225872 Biology of Osteosarcoma (BOOST) Registry and Biobank https://ClinicalTrials.gov/show/NCT03225872 Recruiting University of Minnesota 2050-12-31
NCT03206450 Biospecimen Analysis in Determining Effects of Chemotherapy on Fertility in Osteosarcoma Survivors https://ClinicalTrials.gov/show/NCT03206450 Recruiting Children’s Oncology Group 2021-10-10
NCT03032679 Pain and Impact of Chronic Pain on Function After Total Knee Replacements https://ClinicalTrials.gov/show/NCT03032679 Recruiting Tata Memorial Centre 2020-06-30
NCT02986503 European Study in Bone Sarcoma Patients Over 40 Years https://ClinicalTrials.gov/show/NCT02986503 Completed Italian Sarcoma Group 2015-12-31
NCT00026780 Eligibility Screening for a NCI Pediatric Oncology Branch Research Study https://ClinicalTrials.gov/show/NCT00026780 Enrolling by invitation National Institutes of Health Clinical Center (CC) NA
NCT02383901 A Retrospective Non-intervention Study to Characterize FOlate Rescue Treatment in Osteosarcoma Patients Treated With HDMTX https://ClinicalTrials.gov/show/NCT02383901 Completed Isofol Medical AB 2015-09-30
NCT02132182 Monocyte Phenotypic and Functional Differences https://ClinicalTrials.gov/show/NCT02132182 Completed Duke University 2017-03-23
NCT01807143 Genetic Biomarkers in Tissue Samples From Patients With Osteosarcoma https://ClinicalTrials.gov/show/NCT01807143 Completed Children’s Oncology Group 2012-12-31
NCT01807052 Biomarker Expression in Tissue Samples From Patients With Bone Sarcomas https://ClinicalTrials.gov/show/NCT01807052 Completed Children’s Oncology Group 2016-05-31
NCT01790152 Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment https://ClinicalTrials.gov/show/NCT01790152 Recruiting Children’s Oncology Group 2022-03-30
NCT01374672 Biomarkers in Predicting Response to Chemotherapy in Samples From Young Patients With Osteosarcoma https://ClinicalTrials.gov/show/NCT01374672 Completed Children’s Oncology Group 2011-09-30
NCT04132895 ICONIC: Improving Outcomes Through Collaboration in OsteosarComa https://ClinicalTrials.gov/show/NCT04132895 Recruiting University College, London 2022-10-31
NCT04022512 Accuracy of Deep-learning Algorithm for Detection and Risk Stratification of Lung Nodules https://ClinicalTrials.gov/show/NCT04022512 Recruiting Chinese University of Hong Kong 2022-08-31
NCT03932058 Proteomics Research of Osteosarcoma https://ClinicalTrials.gov/show/NCT03932058 Recruiting Second Affiliated Hospital, School of Medicine, Zhejiang University 2019-09-01
NCT03911245 Osteosarcoma in Patients Older Than 40 Years. Prognostic Factors and Survival https://ClinicalTrials.gov/show/NCT03911245 Completed Fundació Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau 2018-12-31
NCT03839095 Localized Osteosarcoma in Upper Egypt: A Clinical Prediction Model https://ClinicalTrials.gov/show/NCT03839095 Completed Assiut University 2018-07-20
NCT03768076 an Istitution Experience on Parosteal OsTeosarcoma https://ClinicalTrials.gov/show/NCT03768076 Recruiting Istituto Ortopedico Rizzoli 2019-11-01
NCT03737435 Tumor Microenvironment in Patients With Localized Osteosarcoma Treated With Mifamurtide: a Translational Study https://ClinicalTrials.gov/show/NCT03737435 Recruiting Istituto Ortopedico Rizzoli 2020-07-01
NCT03458520 Pediatric PET/MR Image Registry https://ClinicalTrials.gov/show/NCT03458520 Recruiting Stanford University 2020-03-01
NCT03442465 Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas https://ClinicalTrials.gov/show/NCT03442465 Recruiting Memorial Sloan Kettering Cancer Center 2021-02-14
NCT01263405 Monitoring Chemotherapy Response of Soft Tissue Sarcomas and Osteosarcomas Using Diffuse Optical Spectroscopic Imaging https://ClinicalTrials.gov/show/NCT01263405 Completed University of California, Irvine 2014-10-31
NCT01139983 DNA Biomarkers in Samples From Patients With Osteosarcoma and Healthy Volunteers https://ClinicalTrials.gov/show/NCT01139983 Completed Children’s Oncology Group 2016-05-31
NCT01062438 Studying DNA in Tumor Tissue Samples From Patients With Localized or Metastatic Osteosarcoma https://ClinicalTrials.gov/show/NCT01062438 Completed Children’s Oncology Group 2011-09-30
NCT00923650 Informed Consent in Pediatric Cancer Trials https://ClinicalTrials.gov/show/NCT00923650 Completed National Institutes of Health Clinical Center (CC) NA
NCT00899275 Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma https://ClinicalTrials.gov/show/NCT00899275 Active, not recruiting Children’s Oncology Group NA
NCT00898755 Collecting and Storing Tissue From Young Patients With Cancer https://ClinicalTrials.gov/show/NCT00898755 Completed Children’s Oncology Group 2008-07-17
NCT02159443 Pretreatment Anti-Therapeutic Antibodies (PATA) in Patients Treated With hu14.18K322A Antibody https://ClinicalTrials.gov/show/NCT02159443 Active, not recruiting St. Jude Children’s Research Hospital 2019-10-22
NCT01615640 Diffusion Study on Patients With Osteosarcoma https://ClinicalTrials.gov/show/NCT01615640 Completed Klinikum Stuttgart 2019-06-07
NCT00736749 Long-Term Follow-Up of Patients Who Have Participated in Children’s Oncology Group Studies https://ClinicalTrials.gov/show/NCT00736749 Recruiting Children’s Oncology Group 2100-01-31
NCT00686738 Development of Indices Predicting Response to Pre-operative Chemotherapy in Osteosarcoma Patients https://ClinicalTrials.gov/show/NCT00686738 Completed National Cancer Center, Korea 2012-11-30
NCT00631631 Mifamurtide (L-MTP-PE) for High-Risk Osteosarcoma https://ClinicalTrials.gov/show/NCT00631631 Completed Millennium Pharmaceuticals, Inc. 2012-10-31
NCT00588510 Detection of Circulating Osteosarcoma Tumor Cells in the Blood of Patients Using the Polymerase Chain Reaction https://ClinicalTrials.gov/show/NCT00588510 Completed Memorial Sloan Kettering Cancer Center 2011-09-30
NCT00579930 Cytogenetic and Molecular Genetic Studies in Bone Sarcomas https://ClinicalTrials.gov/show/NCT00579930 Completed Memorial Sloan Kettering Cancer Center 2016-02-29
NCT00411060 Clinical Orthopaedic Data Bank (Acute and Chronic) https://ClinicalTrials.gov/show/NCT00411060 Recruiting University of Florida 2021-01-31
NCT00954473 Study of Blood Samples From Patients With Osteosarcoma https://ClinicalTrials.gov/show/NCT00954473 Completed Children’s Oncology Group 2016-05-31
NCT00223184 Genetic Characterisation of High-grade Paediatric Osteosarcomas https://ClinicalTrials.gov/show/NCT00223184 Completed University Hospital, Strasbourg, France NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT04461223 Evaluation of Myocardial Injury After Anthracycline Chemotherapy in Osteosarcoma Patients Using CMR https://ClinicalTrials.gov/show/NCT04461223 Recruiting Second Affiliated Hospital, School of Medicine, Zhejiang University 2021-12-01
NCT03108677 Circulating Exosome RNA in Lung Metastases of Primary High-Grade Osteosarcoma https://ClinicalTrials.gov/show/NCT03108677 Recruiting Ruijin Hospital 2022-05-31
NCT04383288 ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities https://ClinicalTrials.gov/show/NCT04383288 Recruiting Grupo Espanol de Investigacion en Sarcomas 2020-12-31
NCT04181970 Observational Study, for Quality Assessment, of Sarcoma in European and Latin American Multidisciplinary NETWORK https://ClinicalTrials.gov/show/NCT04181970 Recruiting Grupo Espanol de Investigacion en Sarcomas 2022-01-30
NCT03997747 Cancer Genome Study Using Samples From Patients Treated on Clinical Trial SHR1020-SHR-1210-II-OS https://ClinicalTrials.gov/show/NCT03997747 Recruiting Peking University People’s Hospital 2021-07-01
NCT03919539 Epigenetic Biomarker for Advanced Osteosarcoma Using Famitinib and Camrelizumab https://ClinicalTrials.gov/show/NCT03919539 Recruiting Peking University People’s Hospital 2021-06-01
NCT03582527 PD-L1 Expression in Advanced Osteosarcoma https://ClinicalTrials.gov/show/NCT03582527 Recruiting Peking University People’s Hospital 2019-12-31